1604-14-4 2,6-二氯异烟酸乙酯

名称和标识

安全说明

危险性质：非危险化学品

用途与制备

化学合成

产率：96%
合成条件：回流12小时
实验步骤：向79（10g，52mmol）在EtOH（100mL）中的冰冷溶液中加入浓H₂SO₄（5mL）并将反应混合物加热至回流12小时。在真空中除去溶剂。将所得残余物在冰浴中冷却，用NaHCO₃溶液中和并用EtOAc萃取。将有机层干燥并浓缩，得到86（11g，96％）。
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