- BBB permeant
- Yes
- Bioavailability Score
- 0.55
- CYP2D6 inhibitor
- Yes
- Fraction Csp3
- 0.37
- GI absorption
- High
- Log K p (skin permeation)
- -6.43 cm/s
- Log S (Ali)
- -2.93
- Log S (ESOL)
- -3.18
- Log S (SILICOS-IT)
- -4.6
- LogP
- 2.24650
- Molar Refractivity
- 91.76
- Num. H-bond acceptors
- 3.0
- Num. H-bond donors
- 2.0
- Num. heavy atoms
- 22
- Num. rotatable bonds
- 6
- P-gp substrate
- Yes
- PSA
- 43.7 Ų
- Synthetic accessibility
- 2.61
- 密度
- 1.183±0.06 g/cm³ (Predicted)
- 沸点
- 457.6±30.0 °C (760 mmHg)
- 溶解性
- 0.194 mg/ml ; 0.000654 mol/l
- 精确质量
- 297.17300
- 酸度系数(pKa)
- 14.39±0.10 (Predicted)
