化学合成，医药中间体。
医药
合成路线 1（1. 合成：37669-64-0）
产率：95%
合成条件：With sodium tetrahydroborate In methanol at 0℃; for 1 h;
实验步骤：在0℃下，将硼氢化钠（2.2g，59.1mmol）加入到5-溴 - 吡啶-3-甲醛（10.0g，53.7mmol）的MeOH（100mL）悬浮液中。 将混合物在0℃下搅拌1小时，然后通过加入水（5.0mL）淬灭。 蒸发溶剂，得到浅黄色油状物，将其重新溶解在EtOAc中并用水洗涤。 用无水物干燥有机层。 过滤并真空浓缩Na 2 SO 4，得到标题化合物（9.6g，95％），为无色油状物。 MS：188.0和190.0（M + H +）。
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