合成路线 1（1. 合成：7567-63-7）
产率：87%
合成条件：Stage #1: With caesium carbonate In methanol for 16 h; Stage #2: With ammonium chloride In dichloromethane; water
实验步骤：（9）1,3,5-三乙炔基苯。 在氩气下向火焰干燥的烧瓶中加入（8）（2.39mmol，1当量），碳酸铯（4.78mmol，2当量）和甲醇（10mL）。 将反应搅拌16小时。 完成后，解决方案从不透明变为半透明。 真空除去甲醇，将固体在水和二氯甲烷之间分配。 用二氯甲烷（3×20mL）萃取水层。 用氯化铵水溶液（1.0M，2×20mL），水（2×20mL）和盐水（2×20mL）洗涤有机层。 用硫酸钠干燥有机层，过滤，并真空除去。 得到产物，为灰白色软晶体（2.09mmol），产率87％，熔点101-103℃.1H NMR（400MHz，CDCl3）δ7.57（s，3H），3.12（s，3H）。 13 C NMR（100MHz，CDCl 3）δ135.6,122.8,81.6,78.7。 MS（CI +）m / z 151 [M] +。
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