- BBB permeant
- Yes
- Bioavailability Score
- 0.55
- CYP2D6 inhibitor
- Yes
- CYP3A4 inhibitor
- Yes
- Consensus Log P o/w
- 5.15
- GI absorption
- High
- Leadlikeness
- 3.0
- LogP
- 5.76
- MLOGP
- 3.83
- Molar Refractivity
- 144.57
- Number of H-bond acceptors
- 4.0
- Number of H-bond donors
- 1.0
- Number of aromatic heavy atoms
- 12
- Number of heavy atoms
- 35
- Number of rotatable bonds
- 13
- P-gp substrate
- Yes
- PSA
- 67.87 Ų
- SILICOS-IT LogP
- 6.09
- Synthetic accessibility
- 4.2
- WLOGP
- 4.99
- XLogP3
- 5.88
- iLOGP
- 4.96
- 外观
- 白色至类白色固体或粉末
- 密度
- 1.1±0.1 g/cm³
- 折射率
- 1.548
- 水溶解性
- 0.000578 mg/ml;0.0000012 mol/l
- 沸点
- 664.1±55.0 °C (760 mmHg)
- 熔点
- 115-118 °C
- 精确质量
- 480.298798
- 蒸汽压
- 0.0±2.0 mmHg at 25°C
- 酸度系数(pKa)
- 14.79±0.46
- 闪点
- 355.4±31.5 °C