化学合成。
化学合成
合成路线 1（1. 合成：15456-86-7）
产率：87%
合成条件：With hydrazinium sulfate In water at 100℃; for 19 h;
实验步骤：在搅拌下将硫酸肼（2.25g，17,2mmol）溶解在沸水（20mL）中。 通过加料漏斗向该溶液中逐滴加入溴代马来酸酐（2.6mL，28.2mmol），将混合物在回流下加热（100℃）19小时，然后冷却至环境温度。 在中等玻璃料烧结玻璃漏斗上过滤所得白色沉淀，用丙酮（3×5ml）洗涤，真空空气干燥，得到所需产物4-溴-1,2-二氢哒嗪-3,6-二酮（ 2.85g），白色粉末，87％收率（重量分析），熔点262℃。
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