- BBB permeant
- Yes
- Bioavailability Score
- 0.56
- Brenk
- 0.0 alert
- CYP1A2 inhibitor
- No
- CYP2C19 inhibitor
- No
- CYP2C9 inhibitor
- No
- CYP2D6 inhibitor
- No
- CYP3A4 inhibitor
- No
- Egan
- 0.0
- Fraction Csp3
- 0.13
- GI absorption
- High
- Ghose
- None
- Leadlikeness
- 1.0
- Lipinski
- 0.0
- Log K p (skin permeation)
- -5.38 cm/s
- LogP
- 2.58120
- LogS
- -3.86
- Molar Refractivity
- 71.71
- Muegge
- 0.0
- Num. H-bond acceptors
- 4.0
- Num. H-bond donors
- 3.0
- Num. arom. heavy atoms
- 12
- Num. heavy atoms
- 19
- Num. rotatable bonds
- 4
- P-gp substrate
- No
- PAINS
- 0.0 alert
- PSA
- 77.76 Ų
- Synthetic accessibility
- 1.99
- Veber
- 0.0
- 密度
- 1.342 g/cm³
- 折射率
- 1.659
- 沸点
- 453.2 °C (760 mmHg)
- 溶解度
- 0.036 mg/ml ; 0.000139 mol/l
- 熔点
- 192 °C
- 精确质量
- 258.08900
- 蒸汽压
- 5.27E-09 mmHg (25 °C)
- 酸度系数(pKa)
- 3.07±0.30
- 闪点
- 242 °C
