- BBB permeant
- Yes
- Bioavailability Score
- 0.56
- Brenk
- 0.0 alert
- CYP1A2 inhibitor
- No
- CYP2C19 inhibitor
- No
- CYP2C9 inhibitor
- No
- CYP2D6 inhibitor
- No
- CYP3A4 inhibitor
- No
- Egan
- 0.0
- Fraction Csp3
- 0.36
- GI absorption
- High
- Ghose
- None
- Leadlikeness
- 1.0
- Lipinski
- 0.0
- Log K p (skin permeation)
- -6.0 cm/s
- LogP
- 2.09
- LogS
- -2.51 (ESOL)
- Molar Refractivity
- 58.04
- Muegge
- 1.0
- Num. H-bond acceptors
- 2.0
- Num. H-bond donors
- 1.0
- Num. arom. heavy atoms
- 6
- Num. heavy atoms
- 14
- Num. rotatable bonds
- 2
- P-gp substrate
- No
- PAINS
- 0.0 alert
- PSA
- 40.54 Ų
- Synthetic accessibility
- 1.27
- Veber
- 0.0
- 储存条件
- 室温，干燥
- 密度
- 1.2±0.1 g/cm³
- 折射率
- 1.598
- 沸点
- 351.9±25.0 °C (760 mmHg)
- 溶解度
- 0.593 mg/ml ; 0.0031 mol/l
- 熔点
- 87-88.5 °C (Solv: ethyl ether (60-29-7))
- 精确质量
- 191.094635
- 蒸汽压
- 0.0±0.8 mmHg (25 °C)
- 酸度系数(pKa)
- 2.79±0.36 (Predicted)
- 闪点
- 166.6±23.2 °C
