20260-53-1 烟酰氯盐酸盐

危险性质：非危险化学品 危险品属性：非危险品

化学合成。

医药

合成路线 1（1. 合成：20260-53-1）

产率：96% 合成条件：With thionyl chloride In N,N-dimethyl-formamide at 0 - 78℃; for 3 h; Reflux 实验步骤：在无水条件下，在0℃下将烟酸（8.12mmol）和2滴无水DMF加入剧烈搅拌的SOCl 2（10mL）中。 将反应混合物加热至78℃回流3小时，减压蒸发过量的SOCl2后得到黄色固体。 然后加入10mL二乙醚回流1小时，然后过滤，得到白色固体烟酰氯盐酸盐1.388g（产率：96.0％）。 参考文献：

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