- 发生环化及环缩合反应,形成苯并咪唑。
- 储运特性
库房低温通风干燥; 与强氧化剂分开存放
- 灭火剂
水, 二氧化碳, 泡沫, 砂土
有机合成；医药；农药
合成路线 1（1. 合成：95-83-0）
产率：93%
合成条件：With 5%-palladium/activated carbon; hydrazine hydrate In methanol at 20℃; for 0.08 h;
实验步骤：通用方法：向卤化硝基芳烃（1mmol），Pd / C（5％）和MeOH（5mL）的混合物中加入NH 2 NH 2·H 2 O（10mmol），并将所得溶液在80℃回流条件下加热5分钟。 将混合物过滤并真空浓缩。 通过快速柱纯化粗制物质
参考文献：
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合成路线 2（2. 合成：95-83-0）
产率：92%
合成条件：With hydrazine hydrate In ethanol at 70℃; for 4 h;
实验步骤：一般步骤：在典型的反应中，将5.0mg Pd-gCN（5.0wt％Pd）催化剂加入到1.0mM硝基芳烃在乙醇（2mL）和2mM（1.2当量0.07mL）60％的溶液中。 肼水合物。 将混合物在回流温度（70℃）下放入10mL圆底烧瓶中4小时，然后在室温下冷却。 过滤所得物质，滤液经硅胶柱层析，得到相应的产物。 对于二硝基芳烃底物，使用4.0mM（2.4当量0.14mL）60％的水合肼溶液。
参考文献：
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