- BBB permeant
- Yes
- Bioavailability Score
- 0.55
- CYP1A2 inhibitor
- Yes
- CYP2C19 inhibitor
- Yes
- CYP2C9 inhibitor
- Yes
- CYP2D6 inhibitor
- Yes
- CYP3A4 inhibitor
- Yes
- Fraction Csp3
- 0.25
- GI absorption
- High
- Log K p (skin permeation)
- -6.4 cm/s
- Log P o/w (MLOGP)
- 1.99
- Log P o/w (SILICOS-IT)
- 2.45
- Log P o/w (WLOGP)
- 3.1
- Log P o/w (XLOGP3)
- 2.47
- Log P o/w (iLOGP)
- 2.88
- Log S (Ali)
- -3.27
- Log S (ESOL)
- -3.5
- Log S (SILICOS-IT)
- -5.23
- LogP
- 3.72680
- Molar Refractivity
- 85.14
- Num. H-bond acceptors
- 4.0
- Num. H-bond donors
- 0.0
- Num. heavy atoms
- 21
- Num. rotatable bonds
- 3
- P-gp substrate
- No
- PSA
- 54.99 Ų
- Solubility
- 0.0955 mg/ml ; 0.000315 mol/l
- Synthetic accessibility
- 2.58
- 储存条件
- 室温，干燥密封
- 沸点
- 480.4±55.0 °C (760 mmHg)
- 精确质量
- 303.09300
