- BBB permeant
- Yes
- Bioavailability Score
- 0.55
- Brenk
- 0.0 alert
- CYP1A2 inhibitor
- No
- CYP2C19 inhibitor
- No
- CYP2C9 inhibitor
- No
- CYP2D6 inhibitor
- No
- CYP3A4 inhibitor
- No
- Egan
- 0.0
- Fraction Csp3
- 1.0
- GI absorption
- High
- Ghose
- None
- Leadlikeness
- 1.0
- Lipinski
- 0.0
- Log K p (skin permeation)
- -6.28 cm/s
- Log S (Ali)
- -1.87
- Log S (ESOL)
- -1.61
- Log S (SILICOS-IT)
- -1.62
- LogP
- 2.43430
- Molar Refractivity
- 35.14
- Muegge
- 2.0
- Num. H-bond acceptors
- 2.0
- Num. H-bond donors
- 0.0
- Num. arom. heavy atoms
- 0
- Num. heavy atoms
- 8
- Num. rotatable bonds
- 1
- P-gp substrate
- No
- PAINS
- 0.0 alert
- Synthetic accessibility
- 2.16
- Veber
- 0.0
- 密度
- 1.233±0.06 g/cm³ (Predicted)
- 形态
- 固体
- 拓扑极性表面积
- 42.52 Ų
- 水溶解性
- 3.86 mg/ml ; 0.0246 mol/l
- 沸点
- 80 °C (15 Torr)
- 熔点
- 91-92 °C
- 精确质量
- 156.00100
