- BBB permeant
- Yes
- Bioavailability Score
- 0.56
- Brenk
- 0.0 alert
- CYP1A2 inhibitor
- No
- CYP2C19 inhibitor
- No
- CYP2C9 inhibitor
- No
- CYP2D6 inhibitor
- No
- CYP3A4 inhibitor
- No
- Egan
- 0.0
- Fraction Csp3
- 0.3
- GI absorption
- High
- Leadlikeness
- 1.0
- Lipinski
- 0.0
- Log K p (skin permeation)
- -6.16 cm/s
- Log S (Ali)
- -2.14
- Log S (ESOL)
- -2.26
- Log S (SILICOS-IT)
- -2.42
- LogP
- 2.01380
- Molar Refractivity
- 45.44
- Muegge
- 1.0
- Num. H-bond acceptors
- 3.0
- Num. H-bond donors
- 1.0
- Num. arom. heavy atoms
- 6
- Num. heavy atoms
- 13
- Num. rotatable bonds
- 2
- P-gp substrate
- No
- PAINS
- 0.0 alert
- PSA
- 37.30000 Ų
- Synthetic accessibility
- 2.02
- Veber
- 0.0
- 储存条件
- Sealed in dry,Room Temperature
- 密度
- 1.345±0.06 g/cm³ (Predicted)
- 沸点
- 313.9±42.0 °C (Predicted)
- 溶解性
- 0.984 mg/ml ; 0.00546 mol/l
- 精确质量
- 180.05900
- 酸度系数(pKa)
- 4.56±0.10 (Predicted)
