参考文献: [1] Organic and Biomolecular Chemistry, 2007, vol. 5, # 22, p. 3651 - 3656 [2] Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 2007, vol. 62, # 3, p. 397 - 406 [3] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002, vol. 41, # 2, p. 372 - 375 [4] Dalton Transactions, 2016, vol. 45, # 23, p. 9412 - 9418 [5] Journal of the American Chemical Society, 2010, vol. 132, # 49, p. 17366 - 17369 [6] Journal of the Chinese Chemical Society, 2004, vol. 51, # 5 B, p. 1201 - 1208 [7] Journal of the American Chemical Society, 1982, vol. 104, p. 6330 [8] Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1984, vol. 33, p. 777 - 782 [9] Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1984, # 4, p. 844 - 849 [10] Journal of Organic Chemistry, 1993, vol. 58, # 17, p. 4749 - 4753 [11] Tetrahedron, 1995, vol. 51, # 1, p. 77 - 88 [12] Patent: US2007/218010, 2007, A1. Location in patent: Page/Page column 14; 19 [13] Beilstein Journal of Organic Chemistry, 2012, vol. 8, p. 1909 - 1915 [14] Recueil des Travaux Chimiques des Pays-Bas, 1991, vol. 110, # 4, p. 124 - 128 [15] Journal of the Chemical Society. Perkin Transactions 2, 1998, # 1, p. 83 - 88 [16] Journal of the American Chemical Society, 1980, vol. 102, p. 7072 [17] Australian Journal of Chemistry, 1984, vol. 37, # 5, p. 959 - 970 [18] Patent: JP2018/135304, 2018, A. Location in patent: Paragraph 0033; 0034 [19] Inorganic Chemistry Communications, 2012, vol. 21, p. 16 - 20 [20] Patent: US2002/49190, 2002, A1 [21] Chemical Communications, 2010, vol. 46, # 10, p. 1640 - 1642 [22] Synthetic Communications, 1999, vol. 29, # 23, p. 4279 - 4294 [23] Tetrahedron, 1985, vol. 41, # 10, p. 1959 - 1964 [24] Journal of the American Chemical Society, 1986, vol. 108, p. 8302 - 8303 [25] Zeitschrift fuer Naturforschung, B: Chemical Sciences, 2002, vol. 57, # 1, p. 107 - 112 [26] Organic and Biomolecular Chemistry, 2003, vol. 1, # 5, p. 854 - 858 [27] Dalton Transactions, 2013, vol. 42, # 13, p. 4357 - 4360 [28] Inorganic Chemistry, 2014, vol. 53, # 1, p. 468 - 477 [29] Green Chemistry, 2016, vol. 18, # 20, p. 5477 - 5484 [30] Patent: CN106518896, 2017, A. Location in patent: Paragraph 0049; 0050 [31] Chemistry - A European Journal, 2018, vol. 24, # 41, p. 10434 - 10442
路线2：
步骤: A. 1,4,7-三（对甲苯磺酰基）-1,4,7-三氮杂庚烷的合成：在0℃下向搅拌的对甲苯磺酰氯（618g，3.24mol）的吡啶（1500ml）溶液中加入1,4,7-三氮杂庚烷（95.5g，0.926mol）的吡啶溶液（150μl），在干燥的氩气氛下，保持温度<= 50℃，加入需要30分钟，将混合物缓慢冷却至室温并搅拌3小时后，将H₂O（2升）缓慢加入冷却的（冰浴）混合物中，将形成的重白色沉淀物过滤并用H₂O彻底洗涤，将浅黄色固体溶于DMF（3升）中，并在5℃下缓慢加入0.1N HCl（4升），将浆液过滤并变为浅色用H₂O彻底洗涤黄色固体并真空干燥得到产物。
条件: With hydrogenchloride In pyridine; N,N-dimethyl-formamide
产率: 93%
参考文献: [1] Patent: US5874421, 1999, A [2] Patent: US5610293, 1997, A
