86847-84-9 N-(6-氯吡啶-2-基)-2,2-二甲基丙酰胺

运输方式：冰袋运输。危险描述：非危险化学品（sinopharm_reagent）；WGK Germany:3；危险等级:IRRITANT；存储类别:11 - 可燃固体；危险性类别:急性毒性 类别4 经口（chemicalbook）；信号词:Warning；危险性描述:H302；危险标志:GHS07（molbase）。

N-(6-氯吡啶-2-基)-2,2-二甲基丙酰胺主要用于化学合成领域。

化学合成

路线1：

• 步骤：在0℃下，向6-氯-吡啶-2-基胺（0.30g，2.33mmol）和三乙胺（0.41mL，2.92mmol）的无水二氯甲烷悬浮液中加入三氯甲基乙酰氯（0.32mL，2.57mmol）的无水二氯甲烷溶液；将混合物在0℃下搅拌50分钟，然后逐渐升温至室温，反应5小时后倒入水中，分离有机相，水层用二氯甲烷萃取，合并有机相干燥浓缩，经快速色谱法纯化得到产物。
• 条件：With triethylamine In dichloromethane at 0 - 20℃; for 5 h
• 收率：98%
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