未明确具体用途,主要用于医药、农药等领域。
医药; 农药
合成路线 1(1. 合成:141553-09-5)
产率:62%
合成条件:at 80℃; for 6 h;
实验步骤:例9; 1-甲基-2 - ((4aRS,8aRS) - 反式 - 八氢 - 苯并[1,4]恶嗪-4-yD'1H- [4,4']联嘧啶基-6-酮,(化合物编号B69); (IRS .2RS) - 反式-2-苯并氨基环己醇;将环氧环己烷(20g,204mmol)和苄胺(44g,411mmol)的混合物在80℃加热6小时,减压下除去过量的苄胺。 通过硅胶柱色谱法(洗脱液; 5-10%甲醇的氯仿溶液)纯化残余物,得到(1RS,2RS) - 反式-2-苄基氨基环己醇(26g,127mmol,62%),为白色晶体。
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