847728-89-6 [(S)-1-(4-溴苯基)乙基]氨基甲酸叔丁酯

中文名称: [(S)-1-(4-溴苯基)乙基]氨基甲酸叔丁酯
英文名称: tert-Butyl [(S)-1-(4-bromophenyl)ethyl]carbamate
CAS号

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名称和标识

中文名: [(S)-1-(4-溴苯基)乙基]氨基甲酸叔丁酯
英文名: tert-Butyl [(S)-1-(4-bromophenyl)ethyl]carbamate
CAS号: 847728-89-6
分子式: C13H18BrNO2
分子量: 300.19
中文别名: (S)-N-BOC-1-(4-溴苯基)乙胺; (S)-叔丁基1-(4-溴苯基)乙基氨基甲酸酯; [(1S)-1-(4-溴苯基)乙基]氨基甲酸叔丁酯; BOC-S-1-(4-溴苯基)乙胺; (S)-[1-(4-溴-苯基)-乙基]-氨基甲酸叔丁酯
英文别名: (S)-[1-(4-BROMO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER; (S)-tert-butyl 1-(4-bromophenyl)ethylcarbamate; Carbamic acid, [(1S)-1-(4-bromophenyl)ethyl]-, 1,1-dimethylethyl ester; tert-butyl N-[(1S)-1-(4-bromophenyl)ethyl]carbamate; Carbamic acid, N-[(1S)-1-(4-bromophenyl)ethyl]-, 1,1-dimethylethyl ester; (S)-N-Boc-1-(4-bromophenyl)ethanamine; (S)-N-tert-butoxycarbonyl-1-(4-bromophenyl)ethylamine; (S)-tert-Butyl (1-(4-bromophenyl)ethyl)carbamate; (S)-[1-(4-Bromophenyl)ethyl]carbamic acid tert-butyl ester

物化属性

PSA: 38.33 Å²
储存条件: 2-8°C
外观: 白色至类白色固体
密度: 1.282±0.06 g/cm³ (20 °C, 760 Torr)
水溶解性: 0.0424 mg/ml ; 0.000141 mol/l
酸度系数(pKa)

安全信息

安全说明

运输信息：常温运输。危险描述：非危险化学品。

生产及用途

用途与制备

（S）-1-（4-溴苯基）乙基氨基甲酸叔丁酯外观呈白色至淡黄色固体粉末，可用作医药中间体。

医药

路线1：

步骤：向（S）-1-（4-溴苯基）乙胺（0.30g，1.5mmol）的二氯甲烷（5mL）溶液中加入二碳酸二叔丁酯（0.33g，1.5mmol），搅拌混合物在室温下过夜。
条件：20℃；二氯甲烷溶剂
收率：100%
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