95-86-3 2,4-二氨基苯酚

2,4-二氨基苯酚作为重要中间体，广泛应用于医药、农药、染料等领域，具体用途需结合下游产品进一步确定。

医药; 农药; 染料

合成路线 1（1. 合成：95-86-3）

• 产率：96.16%
• 合成条件：Stage #1: With palladium on activated charcoal In methanol at 20℃; for 0.08 h; Autoclave; Inert atmosphere Stage #2: With hydrogen In methanol at 65℃; for 1.50 h; Autoclave
• 实验步骤：在1000ml高压釜中，依次加入100g 2,4-二硝基苯酚，405ml甲醇和6g Pd / C催化剂，将混合物在室温下搅拌5分钟，然后用氮气置换。同时，观察高压釜是否泄漏，升高温度，打开氢气入口阀门，反应温度为65°C，高压釜中的压力保持在0.48 MPa，持续1 h。氢气调节进口阀以使高压釜中的压力保持在0.85MPa 0.5小时，温度降至40℃，更换氮气3次，过滤排出物，回收Pd / C催化剂，并且滤液用氮气保护，目标产物为64.8g，收率为96.16％，纯度为99.2％。
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