6-溴-3,4-二氢-2H-异喹啉-1-酮可用作医药合成中间体。
医药
路线1：
- 步骤: 在0℃下，将甲磺酸加入到溴茚酮在二氯甲烷中的混合物中，分批加入叠氮化钠，加完后搅拌30分钟；加入NaOH的含水混合物直至微碱性，二氯甲烷萃取，减压蒸发有机层，硅胶柱色谱纯化（0至50％EtOAc/己烷，然后0至7％MeOH/CH₂Cl₂）得到产物。
- 条件: Stage #1: 0℃，二氯甲烷，甲磺酸，叠氮化钠；Stage #2: 二氯甲烷，水，NaOH；
- 收率: 61%
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