61-24-5 头孢菌素C

名称和标识

中文名: 头孢菌素C
英文名: Cephalosporin C
CAS号: 61-24-5
分子式: C16H21N3O8S
分子量: 415.42
中文别名: 头孢菌素杂质C; 7-(D-5-氨基-5-羧基戊酰胺基)头孢霉烷酸; (6R,7R)-3-(乙酰氧基甲基)-7-((R)-5-氨基-5-羧基戊酰氨基)-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-甲酸
英文别名: 7-(5-amino-5-carboxyvaleramido)cephalosporanic acid; Cephalosporins-intermediate II; Cefodizime impurity 16; CAPHALOSPORIN C; 5-Thia-1-azabicyclo4.2.0oct-2-ene-2-carboxylic acid, 3-(acetyloxy)methyl-7-(5R)-5-amino-5-carboxy-1-oxopentylamino-8-oxo-, (6R,7R)-; 7-(D-5-Amino-5-carboxyvaleramido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4,2,0]oct-2-ene-2-Carboxylic acid acetate; (7R)-3-[(Acetyloxy)methyl]-7-[[(R)-5-carboxy-5-amino-1-oxopentyl)amino]cepham-3-ene-4-carboxylic acid; Centpropazine; (6R,7R)-3-[(Acetyloxy)methyl]-7-{[(5R)-5-amino-5-carboxypentanoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cephalosporin; Cephalosporn C; Cephalosphorin C; Cefalosporin C; Centropazine; [6R-[6a,7b(R*)]]-3-[(Acetyloxy)methyl]-7-[(5-amino-5-carboxy-1-oxopentyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid; 7-(D-5-Amino-5-carboxyvaleramido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Acetate

安全说明

运输信息：冰袋运输。危险描述：非危险化学品。

用途与制备

头孢菌素C主要用于化学合成，作为制备7-氨基头孢霉烷酸（7-ACA）的中间体；其钠盐二水物为单斜晶体，溶于水，不溶于乙醇、乙醚，水溶液pH2.5-8时稳定，对金葡菌、伤寒杆菌、大肠杆菌有活性，但因抗菌活力低临床未广泛应用。

医药

合成方法：

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